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Important Developments in the Hardening of Babies' Bones in the Womb

The Womb

Bones begin to develop in the womb during the first several weeks of pregnancy

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Ossification

Primary ossification centers occur in the long bones during the 12th week of pregnancy

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Cartilage

The spongy cartilage skeleton progressively changes into solid bone as the pregnancy proceeds.

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Hardening and Mineralization

The bones begin to stiffen and mineralize around the end of the second trimester (about 20 weeks)

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Fetal movement

The motions and interactions of the fetus with the environment contribute to bone strength

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After Birth

Throughout childhood, the bones continue to develop, strengthen, and remodel

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Adolescents

The process of bone formation and growth lasts into puberty.

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